Vascular Disease Foundation - Fighting Vascular Disease... Improving Vascular Health.

Clinical Trials : Aldagen Sponsored Trial


Clinical Research Study for Critical Limb Ischemia

Using stem cells from your own bone marrow!

If you have leg pain at rest, you may be experiencing critical limb ischemia (CLI), the most severe form of peripheral arterial disease (PAD) due to lack of blood flow to the leg. Current treatments for CLI include surgery, angioplasty and, ultimately, amputation.

There has been a great deal of excitement in the research community that stem cells can be used to treat a variety of diseases. Each person stores valuable stem cells in their bone marrow.  Recently in pre-clinical studies, a special population of stem cells taken from bone marrow has shown an ability to repair ischemic damage and grow new blood vessels. Therefore, a patient’s bone marrow stem cells injected back into the patient’s leg may have an ability to help treat critical limb ischemia.

However, there is still too little information available to prove that this approach is a reliable and safe new treatment for CLI. A national clinical study is now underway to determine if using this type of cellular medicine can safely and effectively treat critical limb ischemia. Several patients have already enrolled in the study.

For all research studies, there should be discussion between the patient and physician about the benefits and risks of participation. For this study, only people with rest pain and an ABI of <.5 may qualify to participate. Participation involves study-related medical screening and provides study medication and study-related exams at no cost. The national contact number for this study is 1-919-484-2571 ext. 245 or visit the following web site for more information:  http://www.clinicaltrials.gov/ct/show/NCT00392509?order=1

 

This information is included for patient information only. The Vascular Disease Foundation does not endorse any clinical research studies.